Effects of Echinacea Purpurae Extract on Testicular Ischemia/Reperfusion (I/R) Injury in Rat
Authors
Abstract:
BACKGROUND: Ischemia/reperfusion of tetsis is a male infertility condition which occurs because of oxidation demage. Echinacea purpurea extract (EPE) has antioxidant and protective effect. OBJECTIVES: So, the main purpose of this research was to determine effects of EP extract on testicular ischemia/reperfusion (I/R) injury in rat. METHODS: 50 adult Wistar rats were randomly allocated into five groups: group one as control, group two, 2 hour I/24 hours R period, group three, 1 hour I which after 1 hour of ischemia, rat was injected 25 mg/kg EPE and ischemia continued for an hour, then was followed by 24 hours R period. Groups 4 and 5 were similar to experiment 3, except rats were injected with 50 and 100 mg/kg of EPE, respectively. Then 24 hours later, the left testis was removed for histological and antioxidant enzyme activity including malondialdehyde (MDA), superoxide dismutase (SOD), glutathione peroxidase (GPx) and total antioxidant status (TAS). RESUTLS: Based on the findings, MDA concentration was significantly elevated in I/R rat (P
similar resources
the effect of aqueous extract of garlic on formalin-induced pain in male rats
چکیده اثر عصاره آبی سیر بر درد ناشی از آزمون فرمالین در موش صحرایی نر به کوشش نرگس اسکندری روزبهانی زمینه و هدف: گیاه سیر از خانواده لیلیاسه و گونهallium sativum بومی آسیای میانه بوده و از دوران ،باستان تاکنون به خواص درمانی متفاوت آن مثل: کاهندگی قندخون، کلسترول خون، فشار خون، اثرات مفیدآن بر دستگاه قلبی عروقی و بیماریهای انعقادی خون، اثرات آنتی اکسیداتیو، درمان بیماریهای تنفسی وگوارشی، ا...
15 صفحه اولEffect of pre-treatment with oxytocin on cardiac enzymes in regional ischemiareperfusion injury induced in the rat heart
Introduction: Cardiac preconditioning represents the most potent and consistently reproducible method of rescuing heart tissue from undergoing irreversible ischemic damage. The aim of the present study was to evaluate oxytocin (OT) induced cardioprotection and its signaling pathways on lactate dehydrogenase (LDH) and creatine kinase-MB isoenzyme (CK-MB) in the anesthetized rats. Methods: Ei...
full texteffect of cannabinoids on testicular ischemia-reperfusion injury in rat
anandamide is an endogenous ligand for cannabinoid receptors and has endothelial protective effect against ischemic preconditioning. the purpose of this study was to investigate the effects of cannabinoids on reperfusion injury due to testicular torsion-detorsion (t/d). a total of 36 adult male sprague-dawley rats were divided into 6 groups. testicular ischemia was achieved by twisting the righ...
full textEffects of Magnesium Sulfate Administration on Testicular Ischemia/Reperfusion Injury in Rats
This study aimed at investigating the effects of intraperitoneal (IP) administration of magnesium sulfate (MgSO4) on testicular ischemia-reperfusion (IR) injury in rats. In total, 50 adult Wistar rats were randomly divided into 5 groups. Group 1 received no injection (control); however, group 2 was subjected to 2 h of I and 24 h of R. Subsequently, group 3 was subjected to 2 h of 1, ...
full textthe effects of changing roughness on the flow structure in the bends
flow in natural river bends is a complex and turbulent phenomenon which affects the scour and sedimentations and causes an irregular bed topography on the bed. for the reason, the flow hydralics and the parameters which affect the flow to be studied and understand. in this study the effect of bed and wall roughness using the software fluent discussed in a sharp 90-degree flume bend with 40.3cm ...
My Resources
Journal title
volume 13 issue 3
pages 303- 313
publication date 2019-09-01
By following a journal you will be notified via email when a new issue of this journal is published.
Keywords
Hosted on Doprax cloud platform doprax.com
copyright © 2015-2023